Sunday, April 17, 2011

Osteoporosis

Free eBooks on Osteoporosis

Osteoporosis, or porous bone, is a disease characterized by low bone mass and structural deterioration of bone tissue, leading to bone fragility and an increased risk of fractures of the hip, spine, and wrist. It is often called a “silent” disease because it has no discernable symptoms until there is a bone fracture. Like other tissues in the body, bone tissue is in a state of constant flux – remodeling and rebuilding. There are many influences on bone mass and strength, such as genetics, hormones, physical exercise and diet (especially intake of calcium, phosphate, vitamin D, and other nutrients). Osteoporosis occurs when there are problems with these factors, resulting in more bone loss than bone rebuilding.


This e-book offers a concise yet comprehensive source of all the latest basic research related to osteoporosis in one reference work.  Experts from all areas of osteoporosis research expose readers to genomic and proteomic analysis, histopathology and imaging, as well cellular and molecular mechanisms relevant to assay development and drug discovery.


Osteoporosis is one of the leading causes of morbidity and mortality among the elderly. The rationale for The Osteoporosis Primer is to provide an introductory text that relates the clinical presentation of osteoporosis to its molecular biochemical basis. The text has been organized into four sections that deal with the molecular/ cellular components of bone, the development of peak bone mass, the pathophysiology of aging bone and finally, how all of these relate to the prevention, diagnosis, and treatment of osteoporosis. The international team of authors includes many leading clinicians and scientists who have provided the reader with a concise, yet comprehensive, synopsis of bone development and skeletal homeostasis. This book will be an essential introduction for individuals working on osteoporosis, including students and doctors considering a career related to metabolic bone disease, general practitioners, geriatricians, rheumatologists, and endocrinologists.

Wednesday, April 13, 2011

Nickel Allergy (Eczema)

Free eBooks on Nickel Allergy

MayoClinic.com defines NICKEL ALLERGY and has a lot of free articles on the net which you may browse online.

 
Nickel Allergy will never go away.  Find out why at SQUIDOO.  There are articles that explain how one can get eczema (nickel allergy), and what you can do as precautions.


The Internet Health Library presents Eczema Research, Diet and Lifestyle.  Nickel, which is frequently found in contaminate food, can cause a relapse of contact eczema and also widespread chronic allergic skin reactions in sensitised patients.

Thursday, April 7, 2011

Biologics

Free eBooks on Biologics

What are BIOLOGICS?  Let WIKIPEDIA define it for you.

 This is the first book comprising all relevant aspects for the clinical application of biologics. All biologics currently approved for clinical use are described in a standardized way concentrating on practically relevant aspects such as contra-indications or monitoring needs. The "differential therapy" with biologics namely in the fields of dermatology, rheumatology, gastroenterology, and neurology is described in detail and summarized in treatment algorithms. Shorter sections on the biotechnology behind the biologics as well as safety, regulatory, and pharmaco-economic aspects complement the more clinically-oriented central chapters.


Biologics in Inflammatory Bowel Disease  (Oxford American Pocket Notes)
Scott Plevy, Publisher: OUP USA; 1 Spi edition | ISBN 10: 0195391187 | 2011 | File type: PDF | 63 pages | 1.2 mb.  
Biologic therapies include:(1) naturally occurring or modified biologic compounds such as vaccines (live, live attenuated, or killed microorganisms), hormone extracts, and blood products;(2) recombinant proteins or peptides—for example, granulocyte macrophage colony stimulating factor and growth hormone;(3) monoclonal antibodies and fusion proteins; and (4) antisense oligonucleotides to nucleic acids. These biologic therapies, which are targeted towards specific disease mechanisms, have the potential to provide more effective and safe treatments for human diseases. Clinical trials have demonstrated that inhibition of the cytokine tumour necrosis factor α(TNF) and inhibition of the selective adhesion molecules α4 integrin and α4β7 integrin are effective in the treatment of various forms of the inflammatory bowel diseases (IBD) ulcerative colitis (UC) and Crohn’s disease (CD). It is also clear that drug toxicity related to biologic therapy, including hypersensitivity, serum sickness, autoimmunity, infection, and immunogenicity may occur.
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